Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20471076 | 0.90 | PTGS1 (0.44) | PTGS1PTGS2MGLLFAAHHDAC3 | |
| SCHEMBL17953253 | 0.86 | HDAC3 (0.45) | PTGS1PTGS2MGLLFAAHHDAC3 | |
| SCHEMBL12731358 | 0.86 | MGLL (0.43) | PTGS1PTGS2MGLLFAAHHDAC3 | |
| SCHEMBL22016163 | 0.85 | MGLL (0.53) | PTGS1PTGS2MGLLFAAHHDAC3 | |
| SCHEMBL22422912 | 0.85 | HDAC3 (0.53) | PTGS1PTGS2MGLLFAAHHDAC3 | |
| SCHEMBL13650748 | 0.83 | PTGS1 (0.54) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL16120761 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL17860045 | 0.83 | PTGS1 (0.42) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL23760589 | 0.81 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL16096373 | 0.81 | PTGS1 (0.45) | PTGS1PTGS2MGLLFAAHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019340-A1 | POLYOXAZOLINE ANTIBODY DRUG CONJUGATES | SERINA THERAPEUTICS, INC. (US) | 2016-02-04 | — | — | WO | disclosed |