Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620954 | 0.86 | ALDH1A1 (0.61) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL11467655 | 0.85 | ALDH1A1 (0.53) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL11469397 | 0.83 | ALDH1A1 (0.51) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL31170867 | 0.83 | MEN1 (0.57) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL26690016 | 0.83 | SLC7A5 (0.59) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL2662328 | 0.83 | MEN1 (0.57) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL11458930 | 0.82 | GAA (0.50) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL11460900 | 0.82 | PTGS1 (0.69) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL11463930 | 0.82 | ALDH1A1 (0.50) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL18716081 | 0.82 | LMNA (0.49) | LMNATP53PTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728793-B1 | 9-SUBSTITUTED 8-OXOADENINE COMPOUND | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |