Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228120 | 0.81 | ALDH1A1 (0.33) | DGAT1 | |
| SCHEMBL14174069 | 0.80 | HDAC6 (0.36) | DGAT1HSD17B10TDP1 | |
| SCHEMBL11037398 | 0.76 | TDP1 (0.39) | TET2HSD17B10TDP1 | |
| SCHEMBL322941 | 0.74 | HSD17B10 (0.35) | HSD17B10TDP1 | |
| SCHEMBL18055952 | 0.74 | HSD17B10 (0.39) | HSD17B10TDP1 | |
| SCHEMBL68474 | 0.74 | ELANE (0.38) | DGAT1 | |
| SCHEMBL7860268 | 0.74 | ELANE (0.38) | DGAT1 | |
| Ethylene SCHEMBL18227133 | 0.73 | DGAT1 (0.46) | DGAT1TDP1 | |
| SCHEMBL4725721 | 0.72 | ELANE (0.36) | DGAT1HSD17B10TDP1 | |
| SCHEMBL28050908 | 0.72 | ELANE (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016316-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION A/S (DK) | 2016-02-04 | — | — | WO | disclosed |