SCHEMBL17491815

SCHEMBL17491815

O=S(=O)(OCCO[SiH3])C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032931 0.87 CA2 (0.47) CA2CA1CA9
SCHEMBL4953881 0.80 CA2 (0.43) CA2CA1CA9
SCHEMBL4949086 0.80 CA2 (0.43) CA2CA1CA9
SCHEMBL4949681 0.80 CA2 (0.43) CA2CA1CA9
SCHEMBL1759254 0.78 CA2 (0.42) CA2CA1CA9
SCHEMBL575713 0.77 CA2 (0.44) CA2CA1CA9
SCHEMBL576009 0.77 CA2 (0.44) CA2CA1CA9
SCHEMBL1191830 0.76 CA2 (0.41) CA2CA1CA9
SCHEMBL1759184 0.76 CA2 (0.41) CA2CA1CA9
SCHEMBL1759185 0.76 CA2 (0.41) CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2670758-B1 PROCESS FOR MAKING TRISUBSTITUTED SILYLOXYETHYL TRIFLATES SYNTHON BV (NL) 2022-09-28 EP claimed
US-9938297-B2 Process for the synthesis of everolimus and intermediates thereof Cipia Limited (IN) 2018-04-10 US claimed
US-20170217988-A1 Process for the Synthesis of Everolimus and Intermediates Thereof CIPLA LIMITED (IN) 2017-08-03 US claimed
EP-3166950-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF Cipla Limited (IN) 2017-05-17 EP claimed
WO-2016020664-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF CIPLA LIMITED (IN) 2016-02-11 WO claimed
US-9938297-B2 Process for the synthesis of everolimus and intermediates thereof Cipia Limited (IN) 2018-04-10 US disclosed
US-20170217988-A1 Process for the Synthesis of Everolimus and Intermediates Thereof CIPLA LIMITED (IN) 2017-08-03 US disclosed
EP-3166950-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF Cipla Limited (IN) 2017-05-17 EP disclosed
WO-2016020664-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF CIPLA LIMITED (IN) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217988-A1 Process for the Synthesis of Everolimus and Intermediates Thereof MTOR, RICTOR, RPTOR CA2 3423/4885CA1 4266/4885CA9 1540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.