SCHEMBL1759185

SCHEMBL1759185

COCCOS(=O)(=O)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.41
CA1 P00915 3/20 0.41
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29094937 0.98 CA2 (0.40) CA2CA1
Ammonia Solution, Strong SCHEMBL28134013 0.98 CA2 (0.40) CA2CA1
SCHEMBL18856639 0.94 CA2 (0.40) CA2CA1
Methoxymethane SCHEMBL8159900 0.90 CA2 (0.38) CA2CA1
SCHEMBL1032931 0.87 CA2 (0.47) CA2CA1CA9
SCHEMBL18889097 0.86 CA2 (0.39) CA2CA1CA9
SCHEMBL7450593 0.86 ALDH1A1 (0.41) CA2CA1CA9
SCHEMBL28048598 0.83 CA2 (0.37) CA2CA1
Ethane Dimethane Sulfonate SCHEMBL8875130 0.81 USP2 (0.50) CA2CA1CA9
SCHEMBL4968127 0.80 CA2 (0.34) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565505-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2026-03-03 US disclosed
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-09-11 US disclosed
CN-118184678-A MTORC modulators and uses thereof 艾奥维安制药公司 2024-06-14 CN disclosed
US-20240173305-A1 RAPAMYCIN ANALOGS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 US disclosed
EP-3813946-B1 RAPAMYCIN ANALOGS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-05-22 EP disclosed
EP-3383377-B1 COMPOUNDS AND METHODS FOR INHIBITING PRODUCTION OF TRIMETHYLAMINE PROCTER & GAMBLE (US) 2024-04-17 EP disclosed
CN-117843659-A Rapamycin analogues and uses thereof 詹森药业有限公司 2024-04-09 CN disclosed
CN-113766916-B MTORC modulators and uses thereof 艾奥维安制药公司 2024-04-05 CN disclosed
US-11944605-B2 Rapamycin analogs and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2024-04-02 US disclosed
EP-4302827-A2 RAPAMYCIN ANALOGS AND USES THEREOF JANSSEN Pharmaceutica NV (BE) 2024-01-10 EP disclosed
WO-2003091253-A1 NITROSATED IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2003-11-06 WO disclosed
CN-1452620-A Imidazolo-5-yl-2-anilino-pyrimidines as agents for inhibition of cell proliferation ASTRAZENECA AB (CH) 2003-10-29 CN disclosed
EP-1351958-A1 IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION AstraZeneca AB (SE) 2003-10-15 EP disclosed
EP-1332143-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA Pharma AG (DE) 2003-08-06 EP disclosed
WO-2002034749-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2002-05-02 WO disclosed
WO-2002020512-A1 IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION ASTRAZENECA AB (SE) 2002-03-14 WO disclosed
CN-1231663-A Arthropodicidal and fungicidal cyclic amides DU PONT (US) 1999-10-13 CN disclosed
EP-0934283-A2 ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-11 EP disclosed
WO-1998005652-A2 ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-12 WO disclosed
US-4732977-A BACTERICIDES BRISTOL MYERS COMPANY (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO CA2 1924/4885CA1 4853/4885CA9 3355/4885
US-12565505-B2 mTORC modulators and uses thereof RICTOR, MTOR, RPTOR CA2 2121/4885CA1 4484/4885CA9 3889/4885
US-11944605-B2 Rapamycin analogs and uses thereof RICTOR, MTOR, RPTOR CA2 4583/4885CA1 4755/4885CA9 4287/4885
US-20240173305-A1 RAPAMYCIN ANALOGS AND USES THEREOF RICTOR, MTOR, RPTOR CA2 4583/4885CA1 4755/4885CA9 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.