Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298129 | 0.98 | CYP2A6 (0.52) | CYP2A6FLT3AOC3KDM4EMAPT | |
| SCHEMBL28743701 | 0.81 | CYP2A6 (0.44) | CYP2A6FLT3AOC3KDM4EMAPT | |
| SCHEMBL28238048 | 0.78 | ALDH1A1 (0.36) | MAPTDAOHPGDALDH1A1NPC1 | |
| SCHEMBL1851831 | 0.78 | NPC1 (0.43) | CYP2A6FLT3AOC3KDM4EMAPT | |
| SCHEMBL27075383 | 0.77 | AOC3 (0.52) | CYP2A6FLT3AOC3KDM4EMAPT | |
| SCHEMBL24619687 | 0.77 | CYP19A1 (0.44) | CYP2A6FLT3KDRMEN1KMT2A | |
| SCHEMBL28397626 | 0.77 | KDM4E (0.47) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL28312008 | 0.77 | DAO (0.51) | CYP2A6FLT3AOC3KDM4EMAPT | |
| SCHEMBL28330106 | 0.77 | CDC25B (0.61) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL28488611 | 0.75 | AOC3 (0.50) | CYP2A6FLT3AOC3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396284-B | Benzo-seven-membered nitrogen-oxygen heterocyclic indole-2-carboxamide derivative, preparation method and application thereof | 宁夏医科大学 | 2025-03-25 | — | — | CN | claimed |
| CN-111171040-A | Dihydrofuropyran/pyridoindole derivatives and synthesis method thereof | 常州大学 | 2020-05-19 | — | — | CN | claimed |
| CN-116396284-B | Benzo-seven-membered nitrogen-oxygen heterocyclic indole-2-carboxamide derivative, preparation method and application thereof | 宁夏医科大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-113979915-B | Dopamine D 2 Receptor dual ligand compounds and uses | 常州大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-115745961-A | Phenyl indole compound and preparation and application thereof | 浙江工业大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-115716818-A | Benzamide compound and preparation and application thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113979915-A | Dopamine D2Receptor dibit ligand type compound and application | 常州大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-111171040-A | Dihydrofuropyran/pyridoindole derivatives and synthesis method thereof | 常州大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-109734708-A | Pyrimidine indoles Nur77 receptor modulators and its preparation method and application | 厦门大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-106317043-B | A kind of 2 agonist of Cannabined receptor | 成都理工大学 | 2018-11-02 | — | — | CN | disclosed |
| US-5491153-A | 3-amidoindolyl derivative | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-02-13 | — | — | US | disclosed |
| US-5189054-A | 3-amidoindolyl derivatives and pharmaceutical compositions thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0483881-A1 | 3-Amidoindolyl derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| US-4924004-A | 1-phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1990-05-08 | — | — | US | disclosed |
| US-4814345-A | ANTIARRHYTHMIA AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1989-03-21 | — | — | US | disclosed |
| US-4803198-A | ANTIARRHYTHMIA AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1989-02-07 | — | — | US | disclosed |
| EP-0004400-B1 | PHOTOGRAPHIC DIFFUSION TRANSFER PROCESS AND MATERIAL FOR THE PRODUCTION OF COLOUR IMAGES AND SUITABLE COMPOUNDS THEREFOR | AGFA-GEVAERT N.V. (BE) | 1983-03-16 | — | — | EP | disclosed |
| US-4273855-A | Photographic diffusion transfer process and material for the production of color images and suitable compounds therefor | AGFA-GEVAERT N.V. (BE) | 1981-06-16 | — | — | US | disclosed |
| EP-0004400-A2 | Photographic diffusion transfer process and material for the production of colour images and suitable compounds therefor | AGFA-GEVAERT N.V. (BE) | 1979-10-03 | — | — | EP | disclosed |