Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 13/20 | 0.61 |
| ▸ | APAF1 | O14727 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | CASP3 | P42574 | 5/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.61 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 4/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | UBE2I | P63279 | 2/20 | 0.61 |
| ▸ | GALK1 | P51570 | 1/20 | 0.61 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 6/20 | 0.56 |
| ▸ | TDP2 | O95551 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749199 | 0.77 | CYP2A6 (0.53) | KDM4ECASP3SENP8SENP7SENP6 | |
| SCHEMBL28298129 | 0.75 | CYP2A6 (0.52) | KDM4ECASP3SENP8SENP7SENP6 | |
| SCHEMBL5262034 | 0.73 | CYP2A6 (0.58) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL150458 | 0.72 | KDM4E (0.60) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL29784203 | 0.72 | KDM4E (0.60) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL3968427 | 0.69 | CDC25B (0.64) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL6448568 | 0.68 | KDM4E (0.60) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL1687342 | 0.68 | KDM4E (0.60) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL1719778 | 0.68 | LOXL2 (0.61) | CDC25BAPAF1KDM4ECASP3SENP8 | |
| SCHEMBL1818129 | 0.68 | KDM4E (0.60) | CDC25BAPAF1KDM4ECASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434782-B | A kind of synthetic method of 4- oxyquinoline ketone derivatives and its application in antitumor research | 重庆文理学院 | 2019-11-05 | — | — | CN | disclosed |