SCHEMBL17493267

SCHEMBL17493267

CC(C)c1nc(-c2ccccc2)cc(-c2ccccc2F)c1C=CC1CC(O)CC(=O)O1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 13/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17493265 1.00 HMGCR (0.81) HMGCR
SCHEMBL17493266 1.00 HMGCR (0.81) HMGCR
SCHEMBL9022328 0.91 HMGCR (0.89) HMGCR
Glenvastatin SCHEMBL1660022 0.89 HMGCR (1.00) HMGCR
Glenvastatin SCHEMBL9872411 0.89 HMGCR (1.00) HMGCR
Glenvastatin SCHEMBL10024037 0.89 HMGCR (1.00) HMGCR
SCHEMBL9022892 0.89 HMGCR (1.00) HMGCR
Glenvastatin SCHEMBL49508 0.89 HMGCR (1.00) HMGCR
Glenvastatin SCHEMBL1040744 0.89 HMGCR (1.00) HMGCR
Glenvastatin SCHEMBL1040745 0.89 HMGCR (1.00) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9259872-B2 Multiparticulates EURO-CELTIQUE S.A. (LU) 2016-02-16 US claimed