Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 12/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glenvastatin SCHEMBL1040745 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL29557142 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1040744 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL9872411 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL49508 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1660022 | 1.00 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL10024037 | 1.00 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9527887 | 0.96 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9022328 | 0.94 | HMGCR (0.89) | HMGCR | |
| SCHEMBL9023237 | 0.92 | HMGCR (0.85) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307342-B1 | 3-Demethyl-4-fluoro-mevalonic-acid derivatives, process for their preparation, pharmaceutical preparations based on those compounds, their use and intermediates | HOECHST AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-4925852-A | TREATMENT OR PROPHYLAXIS OF ARTERIOSCLEROSIS OR HYPERCHOLESTEROLEMIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0307342-A2 | 3-Demethyl-4-fluoro-mevalonic-acid derivatives, process for their preparation, pharmaceutical preparations based on those compounds, their use and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-15 | — | — | EP | disclosed |