SCHEMBL17494191

SCHEMBL17494191

COC(=O)C[C@H](NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C)C(=O)COc1c(F)cccc1F

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 19/20 0.54
CASP6 P55212 18/20 0.54
CASP8 Q14790 18/20 0.54
CASP7 P55210 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17494193 1.00 CASP3 (0.54) CASP3CASP6CASP8CASP7
SCHEMBL17494192 1.00 CASP3 (0.54) CASP3CASP6CASP8CASP7
SCHEMBL11896297 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL11896298 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL11896299 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL11911364 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL2878062 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL2878064 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL20870231 0.94 CASP3 (0.49) CASP3CASP6CASP8
SCHEMBL15947165 0.92 CASP3 (0.63) CASP3CASP6CASP8CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11612163-B2 Stabilization of whole blood samples THE GENERAL HOSPITAL CORPORATION (US) 2023-03-28 US claimed
WO-2022123062-A1 BLOCKING CASPASE AND/OR FASL FOR PREVENTING FATAL OUTCOME IN COVID-19 PATIENTS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-16 WO claimed
US-20210007348-A1 STABILIZATION OF WHOLE BLOOD SAMPLES THE GENERAL HOSPITAL CORPORATION 2021-01-14 US claimed
EP-3698628-A1 STABILIZATION OF WHOLE BLOOD SAMPLES The General Hospital Corporation (US) 2020-08-26 EP claimed
EP-3177924-A1 STABILIZATION OF WHOLE BLOOD SAMPLES The General Hospital Corporation (US) 2017-06-14 EP claimed
WO-2016022433-A1 STABILIZATION OF WHOLE BLOOD SAMPLES THE GENERAL HOSPITAL CORPORATION (US) 2016-02-11 WO claimed
US-20250099530-A1 COMPOUND FOR USE IN PREVENTING AND/OR TREATING AN INFECTION CAUSED BY SARS-COV-2 UNIVERSITÉ PARIS CITÉ (FR) 2025-03-27 US disclosed
EP-4469073-A1 COMPOUND FOR USE IN PREVENTING AND/OR TREATING AN INFECTION CAUSED BY SARS-COV-2 Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2024-12-04 EP disclosed
CN-119072326-A Compounds for preventing and/or treating infections caused by SARS-CoV-2 INSERM(法国国家健康医学研究院) 2024-12-03 CN disclosed
US-20240382628-A1 COMPOSITIONS AND METHODS RELATING TO CELLS WITH ADHERED PARTICLES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-11-21 US disclosed
EP-4370160-A1 COMPOSITIONS AND METHODS RELATING TO CELLS WITH ADHERED PARTICLES President And Fellows Of Harvard College (US) 2024-05-22 EP disclosed
WO-2023139182-A1 COMPOUND FOR USE IN PREVENTING AND/OR TREATING AN INFECTION CAUSED BY SARS-COV-2 INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-27 WO disclosed
US-11612163-B2 Stabilization of whole blood samples THE GENERAL HOSPITAL CORPORATION (US) 2023-03-28 US disclosed
WO-2020264313-A1 COMPOSITIONS FOR THE STABILIZATION OF CELL-FREE NUCLEIC ACIDS AND METHODS THEREOF ZYMO RESEARCH CORPORATION (US) 2020-12-30 WO disclosed
EP-3698628-A1 STABILIZATION OF WHOLE BLOOD SAMPLES The General Hospital Corporation (US) 2020-08-26 EP disclosed
US-10750739-B2 Stabilization of whole blood samples THE GENERAL HOSPITAL CORPORATION (US) 2020-08-25 US disclosed
US-20170223949-A1 STABILIZATION OF WHOLE BLOOD SAMPLES THE GENERAL HOSPITAL CORPORATION 2017-08-10 US disclosed
EP-3177924-A1 STABILIZATION OF WHOLE BLOOD SAMPLES The General Hospital Corporation (US) 2017-06-14 EP disclosed
CN-106796219-A The stabilisation of whole blood sample 通用医疗公司 2017-05-31 CN disclosed
WO-2016022433-A1 STABILIZATION OF WHOLE BLOOD SAMPLES THE GENERAL HOSPITAL CORPORATION (US) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099530-A1 COMPOUND FOR USE IN PREVENTING AND/OR TREATING AN INFECTION CAUSED BY SARS-COV-2 ACE2, ACE, SARS1 CASP3 426/4885CASP6 220/4885CASP8 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.