Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17497370 | 1.00 | L3MBTL1 (0.53) | L3MBTL1KLK7PPARGPPARAATM | |
| SCHEMBL2189806 | 0.88 | L3MBTL1 (0.53) | L3MBTL1KLK7ATMALDH1A1LMNA | |
| SCHEMBL2189803 | 0.88 | L3MBTL1 (0.53) | L3MBTL1KLK7ATMALDH1A1LMNA | |
| SCHEMBL17497670 | 0.80 | L3MBTL1 (0.46) | L3MBTL1PPARGATMCNR1CNR2 | |
| SCHEMBL17497671 | 0.80 | L3MBTL1 (0.46) | L3MBTL1PPARGATMCNR1CNR2 | |
| SCHEMBL17497666 | 0.80 | L3MBTL1 (0.46) | L3MBTL1PPARGATMCNR1CNR2 | |
| SCHEMBL17497201 | 0.79 | L3MBTL1 (0.46) | L3MBTL1PPARGPPARA | |
| SCHEMBL17497198 | 0.79 | L3MBTL1 (0.46) | L3MBTL1PPARGPPARA | |
| SCHEMBL12508089 | 0.79 | L3MBTL1 (0.69) | L3MBTL1PPARGPPARA | |
| SCHEMBL2188918 | 0.79 | L3MBTL1 (0.69) | L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | SHH, GLI1, SMO | L3MBTL1 188/4885KLK7 3688/4885PPARG 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.