⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635116 | 0.63 | — | — | |
| SCHEMBL7549500 | 0.60 | — | — | |
| SCHEMBL6784153 | 0.56 | NISCH (0.37) | — | |
| SCHEMBL15099958 | 0.55 | CRBN (0.40) | — | |
| SCHEMBL11133453 | 0.53 | BACE1 (0.41) | — | |
| SCHEMBL15439039 | 0.53 | — | — | |
| SCHEMBL4195110 | 0.53 | — | — | |
| SCHEMBL3201257 | 0.52 | CYP1A2 (0.32) | — | |
| SCHEMBL1338864 | 0.51 | — | — | |
| SCHEMBL160163 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106482-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2024192064-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ PROTEOVANT THERAPEUTICS, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024064316-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 INHIBITORS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-03-28 | — | — | WO | disclosed |
| CN-112876470-B | Method for synthesizing quinazolinone compound under nonmetal catalysis without additive | 中国科学院大连化学物理研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-112876470-A | Method for synthesizing quinazolinone compound under nonmetal catalysis without additive | 中国科学院大连化学物理研究所 | 2021-06-01 | — | — | CN | disclosed |
| EP-3177365-A1 | AGONISTS OF THE AHR RECEPTOR PATHWAY HAVING SEBOSUPPRESSIVE ACTIVITY AND A METHOD FOR IDENTIFYING SAID AGONISTS | Thesan Pharmaceuticals, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016022703-A1 | AGONISTS OF THE AHR RECEPTOR PATHWAY HAVING SEBOSUPPRESSIVE ACTIVITY AND A METHOD FOR IDENTIFYING SAID AGONISTS | THESAN PHARMACEUTICALS, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| CN-101953838-A | Application of rutaecarpine in treating psoriasis | DAI LI | 2011-01-26 | — | — | CN | disclosed |