Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883560 | 0.74 | — | — | |
| SCHEMBL8559331 | 0.72 | NISCH (0.38) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL4273595 | 0.71 | NISCH (0.34) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL779679 | 0.71 | NISCH (0.43) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL13386056 | 0.68 | NISCH (0.37) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL4642439 | 0.67 | CYP11B2 (0.39) | MEN1KMT2A | |
| SCHEMBL14969027 | 0.67 | NISCH (0.37) | NISCHMTORADKALDH1A1BRD4 | |
| SCHEMBL81650 | 0.67 | NISCH (0.59) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL1205638 | 0.66 | — | — | |
| SCHEMBL6844699 | 0.65 | F2RL1 (0.49) | NISCHMTORADKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803367-B2 | ANTICANCER AGENTS; SYNERGISTIC MIXTURES | TAKARA SHUZO CO., LTD. (JP) | 2004-10-12 | — | — | US | disclosed |
| CN-1125023-C | Apoptosis inducer | TAKARA SHUZO CO (JP) | 2003-10-22 | — | — | CN | disclosed |
| US-20030065014-A1 | Substance for inducing apoptosis | TAKARA BIO INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6525082-B1 | 2-hydroxy-4-(1-imidazolyl)-2-cyclopenten-1-one; inhibiting growth of cancer cells | TAKARA SHUZO CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| CN-1281426-A | Substance inducing apoptosis | TAKARA SHUZO CO (JP) | 2001-01-24 | — | — | CN | disclosed |
| EP-1048641-A1 | APOPTOSIS INDUCER | Takara Shuzo Co, Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065014-A1 | Substance for inducing apoptosis | BAX, BCL2, BAD | NISCH 3050/4885MTOR 813/4885ADK 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.