SCHEMBL17499276

SCHEMBL17499276

Cc1cccc(O[Si](C)(C)C)c1N=Cc1cn(C)cn1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499273 1.00 ALDH1A1 (0.30) ALDH1A1LMNAHPGDALOX15TSHR
SCHEMBL16097455 0.87 AMY1A (0.38) ALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL16097452 0.87 AMY1A (0.38) ALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL17499403 0.81 MEN1 (0.31) ALDH1A1
SCHEMBL17499405 0.81 MEN1 (0.31) ALDH1A1
SCHEMBL17499530 0.81 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL17499525 0.81 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL17499307 0.81 TSHR (0.33) ALDH1A1LMNAHPGDALOX15TSHR
SCHEMBL16097677 0.78 NR4A1 (0.46) ALDH1A1LMNAHPGDMAPK1SMN1; SMN2
SCHEMBL16097675 0.78 NR4A1 (0.46) ALDH1A1LMNAHPGDMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed