Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499780 | 0.86 | MAPT (0.49) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL17499778 | 0.86 | MAPT (0.49) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL16095830 | 0.83 | MAPT (0.38) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL16095832 | 0.83 | MAPT (0.38) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL17499428 | 0.78 | POLB (0.41) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL17499591 | 0.77 | MAPT (0.54) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL16095579 | 0.74 | GRIN1 (0.33) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL17499632 | 0.73 | LMNA (0.38) | MAPTLMNAG6PC1ALDH1A1MEN1 | |
| SCHEMBL17499578 | 0.73 | MAPT (0.43) | MAPTLMNATDP1G6PC1ALDH1A1 | |
| SCHEMBL17499801 | 0.72 | NR4A1 (0.41) | MAPTLMNAG6PC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |