Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 11/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096740 | 0.87 | GRIN1 (0.45) | POLBTDP1KMT2ANPC1GRIN1 | |
| SCHEMBL16096741 | 0.87 | GRIN1 (0.45) | POLBTDP1KMT2ANPC1GRIN1 | |
| SCHEMBL16098102 | 0.85 | POLB (0.40) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL16098103 | 0.85 | POLB (0.40) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL17499632 | 0.79 | LMNA (0.38) | KMT2AGRIN1GRIN2BGAAMEN1 | |
| SCHEMBL16098151 | 0.78 | GRIN1 (0.33) | KMT2AGRIN1GRIN2BGAAMEN1 | |
| SCHEMBL17499302 | 0.78 | MAPT (0.38) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL17499534 | 0.77 | POLB (0.40) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL16105006 | 0.77 | LMNA (0.35) | TDP1KMT2ANPC1RAB9AGRIN1 | |
| SCHEMBL17499341 | 0.76 | ALDH1A1 (0.44) | POLBKMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |