Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 3/20 | 0.31 |
| ▸ | FNTB | P49356 | 3/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499352 | 0.88 | MEN1 (0.30) | PDE4AMEN1KMT2ATAAR1FNTA | |
| SCHEMBL28039870 | 0.78 | MET (0.42) | MEN1KMT2ATAAR1CYP1A2LMNA | |
| SCHEMBL17499455 | 0.76 | MEN1 (0.33) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL16097741 | 0.76 | TAAR1 (0.39) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL17499115 | 0.75 | KDM4E (0.40) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL17499789 | 0.74 | MEN1 (0.34) | MEN1KMT2ATAAR1LMNADYRK3 | |
| SCHEMBL28039852 | 0.74 | MET (0.42) | MEN1KMT2ATAAR1CYP1A2LMNA | |
| SCHEMBL16096005 | 0.74 | MEN1 (0.43) | MEN1KMT2ATAAR1CYP11B2DYRK3 | |
| SCHEMBL16097842 | 0.74 | ALDH1A1 (0.46) | MAPK1MEN1KMT2ATAAR1CYP11B1 | |
| SCHEMBL16097183 | 0.73 | MEN1 (0.36) | MEN1KMT2ATAAR1DYRK3CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |