Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095208 | 0.87 | KDM4E (0.40) | KDM4EMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL17499158 | 0.85 | SYK (0.35) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16096607 | 0.85 | GAA (0.33) | KDM4EKMT2A | |
| SCHEMBL16097387 | 0.84 | KDM4E (0.34) | KDM4E | |
| SCHEMBL17499266 | 0.84 | GABRA1 (0.32) | KDM4EMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL16097397 | 0.82 | SCN8A (0.32) | CYP1A2CYP3A4CYP2C9NOTUM | |
| SCHEMBL17499102 | 0.82 | PDE4A (0.31) | NPC1RAB9A | |
| SCHEMBL17499828 | 0.82 | CYP1A2 (0.34) | KDM4EMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL16097834 | 0.81 | NOTUM (0.33) | MEN1KMT2ASMN1; SMN2NOTUM | |
| SCHEMBL17499128 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |