SCHEMBL17499102

SCHEMBL17499102

C[Si](C)(C)Oc1ccccc1N=CCc1ccncn1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16095671 0.87 PDE4A (0.39) PDE4ANPC1
SCHEMBL17499158 0.85 SYK (0.35) NPC1RAB9A
SCHEMBL17499472 0.84 PDE4A (0.31) PDE4A
SCHEMBL17499338 0.82 KDM4E (0.32) NPC1RAB9A
SCHEMBL17499156 0.81 CYP19A1 (0.32)
SCHEMBL17499540 0.80 MEN1 (0.32) NPC1
SCHEMBL17499120 0.80 GABRA1 (0.31)
SCHEMBL16096309 0.79 KDM1A (0.35)
SCHEMBL16097578 0.77 ALDH1A1 (0.38)
SCHEMBL17499494 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed