Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499342 | 1.00 | CYP1B1 (0.34) | CYP1B1ALDH1A1KDM4EHSD17B10CASP1 | |
| SCHEMBL17499644 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL17499647 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL16096904 | 0.84 | ALDH1A1 (0.46) | CYP1B1ALDH1A1KDM4EHSD17B10CASP1 | |
| SCHEMBL16096903 | 0.84 | ALDH1A1 (0.46) | CYP1B1ALDH1A1KDM4EHSD17B10CASP1 | |
| SCHEMBL17499410 | 0.84 | ALDH1A1 (0.46) | CYP1B1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17499406 | 0.84 | ALDH1A1 (0.46) | CYP1B1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17499279 | 0.83 | LMNA (0.38) | CYP1B1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17499282 | 0.83 | LMNA (0.38) | CYP1B1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17499196 | 0.81 | KDM4E (0.33) | CYP1B1ALDH1A1KDM4EHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |