Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499450 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL17499696 | 0.89 | MAPT (0.30) | MAPT | |
| SCHEMBL16097921 | 0.89 | MAPT (0.30) | MAPT | |
| SCHEMBL16097352 | 0.88 | — | — | |
| SCHEMBL16097074 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL16097073 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL16102731 | 0.76 | MAPT (0.41) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL17499111 | 0.75 | TDP1 (0.38) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL17499333 | 0.75 | IDO1 (0.36) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL17499784 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |