Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499241 | 0.89 | KDM4E (0.30) | KDM4E | |
| SCHEMBL16471861 | 0.79 | KDM4E (0.45) | TDP1MEN1KMT2AHSD17B10ALOX15 | |
| SCHEMBL16099266 | 0.77 | RAB9A (0.38) | TDP1MEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL16099267 | 0.77 | RAB9A (0.38) | TDP1MEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL17499356 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2AHSD17B10FGBALOX15 | |
| SCHEMBL17499358 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2AHSD17B10FGBALOX15 | |
| SCHEMBL17499450 | 0.75 | SMN1; SMN2 (0.35) | MEN1KMT2AHSD17B10MAPK1CYP19A1 | |
| SCHEMBL17499448 | 0.75 | SMN1; SMN2 (0.35) | MEN1KMT2AHSD17B10MAPK1CYP19A1 | |
| SCHEMBL16103213 | 0.75 | KDM4E (0.52) | TDP1MEN1KMT2AHSD17B10ALOX15 | |
| SCHEMBL16097752 | 0.75 | KDM4E (0.46) | TDP1MEN1KMT2AMAPK1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |