Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096821 | 0.86 | MEN1 (0.31) | SCN8A | |
| SCHEMBL16097907 | 0.86 | SCN8A (0.44) | SCN8ASYKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17499680 | 0.85 | SCN8A (0.32) | SCN8A | |
| SCHEMBL16097423 | 0.84 | SCN8A (0.42) | SCN8ASYKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17499205 | 0.83 | SYK (0.35) | SYKKDM4EL3MBTL1HRH3 | |
| SCHEMBL16835711 | 0.82 | CYP2C9 (0.45) | SCN8AGAAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL17499574 | 0.81 | SYK (0.38) | SCN8ASYKBRD4KDM4EL3MBTL1 | |
| SCHEMBL16101325 | 0.80 | CYP2C9 (0.32) | CYP2C9HRH3 | |
| SCHEMBL17499702 | 0.78 | PKM (0.37) | SYKCYP2C9MAPT | |
| SCHEMBL17499393 | 0.78 | PKM (0.39) | SYKKDM4ECYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |