Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499550 | 1.00 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL16096026 | 0.88 | CYP1A2 (0.52) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL17499639 | 0.88 | CYP1A2 (0.52) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL16096140 | 0.85 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL17499579 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL17499576 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19LMNAGFER | |
| SCHEMBL17499721 | 0.79 | MET (0.37) | CYP1A2CYP2D6CYP2C19LMNAKMT2A | |
| SCHEMBL17499726 | 0.79 | MET (0.37) | CYP1A2CYP2D6CYP2C19LMNAKMT2A | |
| SCHEMBL16097902 | 0.77 | MET (0.37) | LMNAHPGD | |
| SCHEMBL16097900 | 0.77 | MET (0.37) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |