Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097900 | 1.00 | MET (0.37) | METGSK3BHDAC1HDAC2GRIN1 | |
| SCHEMBL17499740 | 0.87 | GRIN1 (0.42) | METGRIN1GRIN2BHPGD | |
| SCHEMBL17499735 | 0.87 | GRIN1 (0.42) | METGRIN1GRIN2BHPGD | |
| SCHEMBL16096112 | 0.79 | GRIN1 (0.33) | GRIN1GRIN2BHPGD | |
| SCHEMBL16096110 | 0.79 | GRIN1 (0.33) | GRIN1GRIN2BHPGD | |
| SCHEMBL17499165 | 0.78 | GSK3B (0.34) | METGSK3BHDAC1HDAC2LMNA | |
| SCHEMBL17499168 | 0.78 | GSK3B (0.34) | METGSK3BHDAC1HDAC2LMNA | |
| SCHEMBL16103277 | 0.78 | LMNA (0.38) | METGRIN1GRIN2BLMNAHPGD | |
| SCHEMBL17499674 | 0.78 | LMNA (0.38) | METGRIN1GRIN2BLMNAHPGD | |
| SCHEMBL17499721 | 0.77 | MET (0.37) | METLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |