Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499556 | 1.00 | RAB9A (0.46) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL16098003 | 0.85 | NPC1 (0.45) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL16098004 | 0.85 | NPC1 (0.45) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL16097715 | 0.84 | MAPT (0.53) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL16097716 | 0.84 | MAPT (0.53) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL17499752 | 0.82 | RAB9A (0.47) | RAB9ANPC1L3MBTL1PKMATM | |
| SCHEMBL17499379 | 0.77 | POLB (0.32) | ALDH1A1POLBKDM4E | |
| SCHEMBL16098025 | 0.77 | MAPT (0.46) | RAB9ANPC1PKMMAPTGAA | |
| SCHEMBL16098026 | 0.77 | MAPT (0.46) | RAB9ANPC1PKMMAPTGAA | |
| SCHEMBL17499410 | 0.74 | ALDH1A1 (0.46) | RAB9ANPC1L3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |