Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499585 | 1.00 | CTH (0.39) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17499708 | 0.86 | KMT2A (0.38) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17499706 | 0.86 | KMT2A (0.38) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16096518 | 0.86 | ALDH1A1 (0.43) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17499322 | 0.86 | ALDH1A1 (0.43) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17499713 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL17499716 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL17499753 | 0.82 | CTH (0.39) | CTHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17499458 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL17499457 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |