Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499649 | 1.00 | ALDH1A1 (0.34) | ALDH1A1GAAL3MBTL1KDM4EKMT2A | |
| SCHEMBL17499416 | 0.87 | KDM4E (0.32) | ALDH1A1GAAL3MBTL1KDM4EKMT2A | |
| SCHEMBL17499413 | 0.87 | KDM4E (0.32) | ALDH1A1GAAL3MBTL1KDM4EKMT2A | |
| SCHEMBL28039892 | 0.85 | KDM4E (0.31) | ALDH1A1GAAKDM4EKMT2AUSP2 | |
| SCHEMBL17499339 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GAAL3MBTL1KDM4EKMT2A | |
| SCHEMBL17499337 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GAAL3MBTL1KDM4EKMT2A | |
| SCHEMBL16096221 | 0.80 | JAK2 (0.37) | ALDH1A1KDM4EKMT2AMEN1MET | |
| SCHEMBL16096219 | 0.80 | JAK2 (0.37) | ALDH1A1KDM4EKMT2AMEN1MET | |
| SCHEMBL16101361 | 0.78 | PDCD1LG2 (0.35) | ALDH1A1GAAKMT2AMEN1HSD17B10 | |
| SCHEMBL17499198 | 0.76 | CYP1B1 (0.46) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |