SCHEMBL28039892

SCHEMBL28039892

Cc1cccc(N=Cc2cnn(C)c2)c1O[SiH](C)C.[H+]

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MET P08581 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499649 0.85 ALDH1A1 (0.34) KDM4EMEN1USP2ALDH1A1GAA
SCHEMBL17499648 0.85 ALDH1A1 (0.34) KDM4EMEN1USP2ALDH1A1GAA
SCHEMBL17499413 0.82 KDM4E (0.32) KDM4EMEN1USP2ALDH1A1GAA
SCHEMBL17499416 0.82 KDM4E (0.32) KDM4EMEN1USP2ALDH1A1GAA
SCHEMBL28039900 0.82 MET (0.30) MET
SCHEMBL16100969 0.79 GABRA1 (0.32)
SCHEMBL28039990 0.78 CYP1B1 (0.32) MET
SCHEMBL28040325 0.78 KDM4E (0.31) KDM4EMET
SCHEMBL28040306 0.76 CHEK1 (0.32)
SCHEMBL17499628 0.75 DHX9 (0.32) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209268-A Heterocyclic imine functionalized polymers BRIDGESTONE CORP 2015-12-30 CN disclosed