Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607509 | 1.00 | HSP90AA1 (0.41) | HSP90AA1HKDC1GRM5DUSP3PTPN11 | |
| SCHEMBL16099405 | 0.86 | MAPT (0.44) | HSP90AA1HKDC1GRM5DUSP3PTPN11 | |
| SCHEMBL17499257 | 0.84 | GRM5 (0.38) | GRM5MAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL16098051 | 0.83 | HTT (0.33) | HSP90AA1GRM5P2RX7ALDH1A1LMNA | |
| SCHEMBL17499449 | 0.82 | HSP90AA1 (0.40) | HSP90AA1HKDC1GRM5DUSP3PTPN11 | |
| SCHEMBL17499517 | 0.81 | KDM4E (0.51) | HKDC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL17499799 | 0.81 | KDM4E (0.33) | MAPTALDH1A1LMNAHSD17B10RAB9A | |
| SCHEMBL17499699 | 0.81 | ADRA2A (0.33) | MAPTALDH1A1LMNAHSD17B10RAB9A | |
| SCHEMBL17499485 | 0.80 | KMT2A (0.36) | MAPTALDH1A1LMNAHSD17B10RAB9A | |
| SCHEMBL17499508 | 0.78 | HCRTR1 (0.31) | MAPTALDH1A1LMNAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |