Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098487 | 0.86 | MAPT (0.42) | HCRTR1HCRTR2ALDH1A1MAPTLMNA | |
| SCHEMBL17499116 | 0.86 | KDM4E (0.38) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499270 | 0.86 | LMNA (0.31) | LMNASMN1; SMN2HTT | |
| SCHEMBL16096946 | 0.84 | SMN1; SMN2 (0.35) | ALDH1A1MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL17499097 | 0.83 | ALDH1A1 (0.30) | ALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL17499476 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499799 | 0.79 | KDM4E (0.33) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL22607509 | 0.78 | HSP90AA1 (0.41) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499669 | 0.78 | HSP90AA1 (0.41) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499371 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |