Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.37 |
| ▸ | CLK1 | P49759 | 5/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.35 |
| ▸ | CLK2 | P49760 | 3/20 | 0.35 |
| ▸ | CLK3 | P49761 | 3/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.35 |
| ▸ | DYRK4 | Q9NR20 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499687 | 1.00 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16101437 | 0.88 | ALDH1A1 (0.45) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16101441 | 0.88 | ALDH1A1 (0.45) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103586 | 0.81 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103588 | 0.81 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL17499714 | 0.80 | DYRK1A (0.37) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL17499718 | 0.79 | NOTUM (0.37) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL17499785 | 0.78 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL17499792 | 0.78 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL17499312 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |