Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.33 |
| ▸ | CLK1 | P49759 | 5/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.32 |
| ▸ | CLK2 | P49760 | 3/20 | 0.32 |
| ▸ | CLK3 | P49761 | 3/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102217 | 0.89 | SHBG (0.43) | NOTUMSHBGDYRK1ACLK1CLK4 | |
| SCHEMBL16103586 | 0.89 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103588 | 0.89 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103543 | 0.80 | BCHE (0.34) | MAPTTHRBPKMNPC1RAB9A | |
| SCHEMBL17499687 | 0.79 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL17499683 | 0.79 | NOTUM (0.38) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103153 | 0.78 | MAPT (0.42) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL16103156 | 0.78 | MAPT (0.42) | NOTUMDYRK1ACLK1CLK4DYRK1B | |
| SCHEMBL17499697 | 0.77 | CYP1A2 (0.30) | SMN1; SMN2 | |
| SCHEMBL17499714 | 0.76 | DYRK1A (0.37) | NOTUMDYRK1ACLK1CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |