Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499768 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499515 | 0.86 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499512 | 0.86 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499425 | 0.77 | GRIN2B (0.40) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL16101467 | 0.77 | PDE4A (0.40) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499333 | 0.77 | IDO1 (0.36) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL17499422 | 0.77 | GRIN2B (0.40) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL17499723 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499727 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499335 | 0.75 | SIGMAR1 (0.43) | ALDH1A1MEN1KMT2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |