Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386671 | 0.79 | METAP2 (0.42) | DYRK1ACYP3A4CDK4CCND1CCNT1 | |
| SCHEMBL31386812 | 0.76 | PARP1 (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9715623 | 0.75 | PARP1 (0.54) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL30577453 | 0.75 | PARP1 (0.54) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL19211570 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL29853502 | 0.71 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL26768225 | 0.71 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL10670024 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL405147 | 0.70 | CHEK1 (0.47) | KDM4EHPGDLMNAMEN1KMT2A | |
| SCHEMBL436095 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016024096-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2016-02-18 | — | — | WO | disclosed |