SCHEMBL17499990

SCHEMBL17499990

C=C[C@H]1CC[C@H](NC(=O)OCc2ccccc2)CC1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
GAA P10253 1/20 0.69
TSHR P16473 1/20 0.66
EPHX1 P07099 1/20 0.59
DPP4 P27487 6/20 0.54
DPP7 Q9UHL4 6/20 0.54
KCNH2 Q12809 3/20 0.54
CTSL P07711 1/20 0.53
CTSB P07858 1/20 0.53
CTSK P43235 1/20 0.53
TGM2 P21980 3/20 0.53
F13A1 P00488 1/20 0.53
TGM1 P22735 1/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
TLR4 O00206 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499991 1.00 ALDH1A1 (0.69) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL381922 0.89 ALDH1A1 (0.85) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL3948461 0.89 ALDH1A1 (0.85) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL3948456 0.89 ALDH1A1 (0.85) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL2558255 0.88 ALDH1A1 (0.71) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL2558257 0.88 ALDH1A1 (0.71) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL3197917 0.88 ALDH1A1 (0.71) ALDH1A1GAATSHREPHX1DPP4
Hydrochloric Acid SCHEMBL28135182 0.87 ALDH1A1 (0.83) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL761181 0.83 ALDH1A1 (0.76) ALDH1A1GAATSHREPHX1DPP4
SCHEMBL9555876 0.83 ALDH1A1 (0.76) ALDH1A1GAATSHREPHX1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016024096-A1 ANTIBACTERIAL COMPOUNDS REDX PHARMA PLC (GB) 2016-02-18 WO disclosed