Citric Acid

SCHEMBL17500032

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nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3A GSK3B HRH2 IMPA1

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	CA4	P22748	3/20	0.89

▸	ALDH1A1	P00352	1/20	0.33

▸	CASP1	P29466	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Citric Acid SCHEMBL1231114	1.00	CA4 (0.89)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL10699295	0.97	CA4 (0.84)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL29587574	0.97	CA4 (0.94)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL22686437	0.97	CA4 (0.94)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL42945	0.97	CA4 (0.94)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL1291555	0.97	CA4 (0.94)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL23012792	0.94	CA4 (0.89)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL20668544	0.94	CA4 (0.89)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL2235356	0.94	CA4 (1.00)	CA4ALDH1A1CASP1
Citric Acid SCHEMBL20668547	0.94	CA4 (0.89)	CA4ALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3180306-A2	ELECTROLYTIC PROCESS FOR PREPARATION OF METAL CARBOXYLATE COMPLEXES	Infinium Precious Resources Ltd. (IN)	2017-06-21	—	—	EP	disclosed
WO-2016024285-A2	ELECTROLYTIC PROCESS FOR PREPARATION OF METAL CARBOXYLATE COMPLEXES	INFINIUM PRECIOUS RESOURCES LTD. (IN)	2016-02-18	—	—	WO	disclosed