Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL17500032 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL10699295 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668544 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL2235356 | 0.94 | CA4 (1.00) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668547 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082175-A1 | EGGSHELL-TYPE CATALYST, MODIFIED CARRIER, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国石油化工股份有限公司 | 2025-04-24 | — | — | WO | claimed |
| CN-119857480-A | Ultrathin eggshell type high-dispersion catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-22 | — | — | CN | claimed |
| US-20240246067-A1 | HIGHLY DISPERSED PALLADIUM CATALYSTS | JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) | 2024-07-25 | — | — | US | claimed |
| EP-4334029-A1 | HIGHLY DISPERSED PALLADIUM CATALYSTS | Johnson Matthey Public Limited Company (GB) | 2024-03-13 | — | — | EP | claimed |
| US-11713286-B2 | Butadiene telomerization catalyst preparation and use thereof | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-08-01 | — | — | US | claimed |
| WO-2023285793-A1 | HIGHLY DISPERSED PALLADIUM CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2023-01-19 | — | — | WO | claimed |
| US-20220213006-A1 | BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-07-07 | — | — | US | claimed |
| CN-107438630-B | Butadiene short-chain polymerization catalyst and preparation thereof | 陶氏环球技术有限责任公司 | 2020-09-15 | — | — | CN | claimed |
| CN-109137050-B | Graphene-doped modified interconnection belt or bus belt and preparation method thereof | 新昌县鸿吉电子科技有限公司 | 2020-07-17 | — | — | CN | claimed |
| EP-3280690-B1 | BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-06-19 | — | — | EP | claimed |
| US-20180072637-A1 | BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-03-15 | — | — | US | claimed |
| EP-3280690-A1 | BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF | Dow Global Technologies LLC (US) | 2018-02-14 | — | — | EP | claimed |
| WO-2016164258-A1 | BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-10-13 | — | — | WO | claimed |
| US-20100217052-A1 | Catalyst For The Selective Hydrogenation Of Acetylenic Hydrocarbons And Method For Producing Said Catalyst | SUD-CHEMIE AG (DE) | 2010-08-26 | — | — | US | claimed |
| US-5405583-A | Solid state sensor for carbon monoxide | FCI - FIBERCHEM, INC. (US) | 1995-04-11 | — | — | US | claimed |
| US-5346671-A | Redox systems | FCI - FIBERCHEM, INC. (US) | 1994-09-13 | — | — | US | claimed |
| US-5135900-A | Aqueous solution of palladium compound and water soluble phosphine ligand associated with nitrile solvent; catalysts for nucleophilic substitution | RHONE-POULENC SANTE (FR) | 1992-08-04 | — | — | US | claimed |
| US-4366035-A | Electrodeposition of gold alloys | ENGELHARD CORPORATION (US) | 1982-12-28 | — | — | US | claimed |
| EP-0015909-A1 | A METHOD OF PRODUCING THROMBOSIS-RESISTANT SURFACES | THIN CONDUCTIVE COATING OSTERMALM (SE) | 1980-10-01 | — | — | EP | claimed |
| WO-1979000638-A1 | A METHOD OF PRODUCING THROMBOSIS-RESISTANT SURFACES | THIN CONDUCTIVE COATING OESTER (SE) | 1979-09-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713286-B2 | Butadiene telomerization catalyst preparation and use thereof | TELO2, TERT, TPR | CA4 4334/4885ALDH1A1 954/4885CASP1 4192/4885 |
| US-20180072637-A1 | BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF | TELO2, TERT, POT1 | CA4 4255/4885ALDH1A1 824/4885CASP1 4355/4885 |
| US-20220213006-A1 | BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF | TELO2, TERT, TPR | CA4 4334/4885ALDH1A1 954/4885CASP1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.