Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620191 | 0.81 | MAOB (0.37) | MAOBNFE2L2SLC6A4ACHEPPARG | |
| SCHEMBL3724795 | 0.80 | MAOB (0.44) | MAOBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11613784 | 0.79 | MAOB (0.40) | MAOBNFE2L2SLC6A4ACHEMRGPRX4 | |
| SCHEMBL10294030 | 0.79 | NFE2L2 (0.43) | MAOBNFE2L2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11515724 | 0.78 | NFE2L2 (0.38) | MAOBNFE2L2SLC6A4ACHEPPARG | |
| SCHEMBL16144539 | 0.77 | MAOB (0.42) | MAOBNFE2L2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7018083 | 0.77 | CA4 (0.39) | SLC6A2PPARGPPARA | |
| SCHEMBL246293 | 0.75 | MAOB (0.40) | MAOBNFE2L2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7940650 | 0.75 | NFE2L2 (0.39) | MAOBNFE2L2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL22477852 | 0.74 | NR4A1 (0.40) | MAOBPPARGPPARAMRGPRX4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022569-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | BLUEPRINT MEDICINES CORPORATION (US) | 2016-02-11 | — | — | WO | disclosed |