Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254534 | 0.80 | GPR3 (0.50) | NFE2L2 | |
| SCHEMBL29435934 | 0.80 | GPR3 (0.50) | NFE2L2 | |
| SCHEMBL10294030 | 0.78 | NFE2L2 (0.43) | NFE2L2SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL246293 | 0.78 | MAOB (0.40) | NFE2L2SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL16144539 | 0.77 | MAOB (0.42) | NFE2L2SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL13144294 | 0.75 | CETP (0.52) | — | |
| SCHEMBL17501722 | 0.75 | MAOB (0.38) | NFE2L2SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL27383227 | 0.75 | SLC22A12 (0.43) | — | |
| SCHEMBL9501529 | 0.75 | LMNA (0.52) | NFE2L2SLC6A2SLC6A4SLC6A3PPARG | |
| SCHEMBL11685732 | 0.74 | ACHE (0.56) | SLC6A2SLC6A4SLC6A3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |