Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366364 | 0.86 | — | — | |
| SCHEMBL25112391 | 0.82 | TSHR (0.38) | KDM4EMAPTTSHR | |
| SCHEMBL18758459 | 0.81 | GRIN2D (0.45) | TSHR | |
| SCHEMBL18292827 | 0.79 | ACHE (0.42) | ACHEKDM4EMAPT | |
| SCHEMBL12714287 | 0.79 | TSHR (0.43) | TSHR | |
| SCHEMBL18292730 | 0.78 | S1PR1 (0.30) | — | |
| SCHEMBL63159 | 0.76 | ACHE (0.62) | ACHEKDM4ECASP6MAPTTSHR | |
| SCHEMBL22102724 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL18292655 | 0.74 | — | — | |
| SCHEMBL23784698 | 0.74 | ACHE (0.48) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982679-A1 | IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE | Idera Pharmaceuticals, Inc. (US) | 2016-02-10 | — | — | EP | disclosed |