Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12026106 | 0.86 | MIF (0.33) | TSHRNOS3NOS1HPGDTRPA1 | |
| SCHEMBL12630761 | 0.79 | TRPA1 (0.52) | CA1CA2CA12CA4CA5A | |
| SCHEMBL17506714 | 0.79 | ACHE (0.42) | TSHR | |
| SCHEMBL18758459 | 0.77 | GRIN2D (0.45) | TSHRNOS3NOS1PRSS1PRSS2 | |
| SCHEMBL41775 | 0.76 | TSHR (0.67) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL16503463 | 0.74 | CYP1A2 (0.43) | — | |
| SCHEMBL12463807 | 0.74 | MIF (0.52) | — | |
| SCHEMBL18815313 | 0.74 | PRSS1 (0.44) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL15308709 | 0.74 | — | — | |
| SCHEMBL11296929 | 0.74 | HRH3 (0.50) | CA1CA2CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534136-B1 | METHODS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9572854-B2 | Treatment of protein degradation disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3048124-A1 | ALIPHATIC POLYCARBONATE HAVING LONG CHAIN BRANCH AND AROMATIC POLYESTER COPOLYMER THEREOF | Lotte Chemical Corporation (KR) | 2016-07-27 | — | — | EP | disclosed |
| EP-2308914-A1 | POLYCARBONATE DIOL AND POLYCARBONATE DIOL COPOLYMER | Ube Industries, Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| EP-2256144-A1 | POLYLACTIC ACID RESIN, POLYLACTIC ACID RESIN COMPOSITION, MOLDED BODY OF POLYLACTIC ACID RESIN OR POLYLACTIC ACID RESIN COMPOSITION, AND METHOD FOR PRODUCING POLYLACTIC ACID RESIN | Mitsui Chemicals, Inc. (JP) | 2010-12-01 | — | — | EP | disclosed |