Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041731 | 0.92 | NPC1 (0.40) | NPC1RAB9AALDH1A1KMT2APDE10A | |
| SCHEMBL17507332 | 0.91 | NPC1 (0.49) | NPC1RAB9AALDH1A1KMT2APDE10A | |
| SCHEMBL20041552 | 0.90 | NPC1 (0.41) | NPC1RAB9AALDH1A1KMT2AMAPK1 | |
| SCHEMBL20041422 | 0.86 | NPC1 (0.44) | NPC1RAB9AALDH1A1MAPK1KDM4E | |
| SCHEMBL17507388 | 0.83 | NPC1 (0.46) | NPC1RAB9AALDH1A1KMT2AMAPK1 | |
| SCHEMBL17507365 | 0.82 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1KMT2AMAPK1 | |
| SCHEMBL20041609 | 0.81 | NPC1 (0.45) | NPC1RAB9AALDH1A1KMT2AKDM4E | |
| SCHEMBL17507245 | 0.80 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL20041550 | 0.80 | NPC1 (0.48) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL17507379 | 0.80 | NPC1 (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |
| EP-2982676-A1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | Idemitsu Kosan Co., Ltd. (JP) | 2016-02-10 | — | — | EP | disclosed |