Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2215952 | 0.86 | HDAC8 (0.63) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL17507485 | 0.85 | NPC1 (0.66) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL12435942 | 0.85 | NPC1 (0.57) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL17507496 | 0.82 | HDAC8 (0.62) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7150002 | 0.82 | HDAC8 (0.67) | NPC1RAB9ATP53SMN1; SMN2HDAC8 | |
| SCHEMBL17512400 | 0.81 | HDAC8 (0.63) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL17512425 | 0.79 | HDAC8 (0.60) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6818005 | 0.79 | NPC1 (0.68) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL28520115 | 0.79 | ACHE (0.56) | NPC1RAB9ATP53ALDH1A1HDAC8 | |
| SCHEMBL12435941 | 0.78 | NPC1 (0.56) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351731-B1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2016-02-10 | — | — | EP | disclosed |