Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521848 | 0.90 | HDAC8 (0.60) | ACHENPC1RAB9APDE4BPDE4D | |
| SCHEMBL17507482 | 0.79 | NPC1 (0.61) | NPC1RAB9APDE4BPDE4DMEN1 | |
| SCHEMBL7868896 | 0.78 | NPC1 (0.83) | NPC1RAB9APDE4BALDH1A1MAPT | |
| SCHEMBL31377084 | 0.74 | KMT2A (0.54) | PDE4BPDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL2498219 | 0.74 | KMT2A (0.54) | PDE4BPDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL31377083 | 0.74 | KMT2A (0.54) | PDE4BPDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL7194819 | 0.74 | KMT2A (0.65) | NPC1RAB9APDE4BMEN1KMT2A | |
| SCHEMBL3736129 | 0.73 | CTNNB1 (0.78) | ACHENPC1RAB9APDE4BPDE4D | |
| SCHEMBL11436374 | 0.72 | NPC1 (0.73) | NPC1RAB9APDE4BMEN1KMT2A | |
| SCHEMBL28650786 | 0.72 | LMNA (0.76) | NPC1RAB9APDE4BKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321440-B | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-112321440-A | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-02-05 | — | — | CN | disclosed |