Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435969 | 0.83 | MAPKAPK2 (0.43) | MAPTSMN1; SMN2MAPK1AHRKMT2A | |
| SCHEMBL13175830 | 0.78 | MEN1 (0.52) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL2217357 | 0.77 | HDAC8 (0.64) | MAPTSMN1; SMN2MAPK1AHRHDAC1 | |
| SCHEMBL6361625 | 0.76 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2MAPK1ALDH1A1TSHR | |
| SCHEMBL17507527 | 0.75 | MAPT (0.56) | MAPTSMN1; SMN2MAPK1AHRHDAC1 | |
| SCHEMBL2215952 | 0.75 | HDAC8 (0.63) | MAPTSMN1; SMN2MAPK1AHRHDAC1 | |
| SCHEMBL2217242 | 0.75 | MAPT (0.56) | MAPTSMN1; SMN2MAPK1AHRHDAC1 | |
| SCHEMBL2217173 | 0.75 | LTB4R (0.66) | MAPTSMN1; SMN2MAPK1AHRHDAC1 | |
| SCHEMBL7414376 | 0.74 | PDE4D (0.66) | — | |
| SCHEMBL2218409 | 0.73 | KMT2A (0.72) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351731-B1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2016-02-10 | — | — | EP | disclosed |