Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16507172 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL2848321 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL3697056 | 0.83 | PARP10 (0.53) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL30644979 | 0.81 | MAOA (0.50) | ALDH1A1LMNASMN1; SMN2TTRMAPT | |
| SCHEMBL1746624 | 0.81 | MAOA (0.50) | ALDH1A1LMNASMN1; SMN2TTRMAPT | |
| SCHEMBL12578071 | 0.80 | FFAR1 (0.63) | KMT2AFFAR1 | |
| SCHEMBL3970300 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL17508212 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL505416 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 | |
| SCHEMBL5050902 | 0.76 | PARP10 (0.65) | ALDH1A1KDM4ECYP2A6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |