SCHEMBL17508335

SCHEMBL17508335

COC(=O)C(C)(N)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.38
KCNN4 O15554 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28467641 0.98 DGAT1 (0.37) DGAT1KCNN4
Hydrochloric Acid SCHEMBL28467640 0.98 DGAT1 (0.37) DGAT1KCNN4
SCHEMBL4511104 0.83 DGAT1 (0.44) DGAT1KCNN4SMN1; SMN2
SCHEMBL4372797 0.83 DGAT1 (0.44) DGAT1KCNN4SMN1; SMN2
SCHEMBL4372798 0.83 DGAT1 (0.44) DGAT1KCNN4SMN1; SMN2
SCHEMBL23277645 0.78 KCNN4 (0.35) DGAT1KCNN4SMN1; SMN2
SCHEMBL27912076 0.78 KCNN4 (0.35) DGAT1KCNN4SMN1; SMN2
SCHEMBL26914951 0.77
SCHEMBL27371179 0.76 DGAT1 (0.38) DGAT1KCNN4
SCHEMBL6596388 0.76 MMP8 (0.44) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016019588-A1 OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE THE BROAD INSTITUTE, INC. (US) 2016-02-11 WO disclosed