Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.50 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30164507 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL2773901 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL29033070 | 0.96 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EGLAGAA | |
| Iodide SCHEMBL3905318 | 0.96 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EGLAGAA | |
| Biphenyl SCHEMBL28506015 | 0.93 | PDE10A (0.54) | ALDH1A1HPGDKDM4EGLAGAA | |
| Boric Acid SCHEMBL30999668 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EGLAGAA | |
| Quinaldine SCHEMBL27595746 | 0.89 | CYP1A2 (0.59) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL28328127 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EGLAGAA | |
| Nitric Acid SCHEMBL9696991 | 0.86 | KDM4E (0.48) | ALDH1A1HPGDKDM4EGLAGAA | |
| Phenylboronic Acid SCHEMBL28563406 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108350466-B | Methods and compositions for determining pH | 芝加哥大学 | 2022-06-24 | — | — | CN | disclosed |
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | ACHE 114/4885P2RY12 451/4885ALDH1A1 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.