Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508483 | 1.00 | HPGD (0.33) | HPGDHSD17B10HTTALOX15GFER | |
| SCHEMBL17524536 | 1.00 | HPGD (0.33) | HPGDHSD17B10HTTALOX15GFER | |
| SCHEMBL24638869 | 0.86 | HPGD (0.38) | HPGDHSD17B10HTTALOX15GFER | |
| SCHEMBL17929419 | 0.86 | NOX1 (0.31) | HTTALOX15 | |
| SCHEMBL2927453 | 0.78 | GAA (0.32) | — | |
| SCHEMBL2927456 | 0.78 | GAA (0.32) | — | |
| SCHEMBL19656322 | 0.74 | — | — | |
| SCHEMBL19965792 | 0.74 | ERN1 (0.32) | HPGDMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL7895215 | 0.67 | HPGD (0.44) | HPGDHSD17B10HTTALOX15GFER | |
| SCHEMBL7895218 | 0.67 | HPGD (0.44) | HPGDHSD17B10HTTALOX15GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016021742-A1 | HETEROCYCLIC COMPOUNDS AS EP4 RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-02-11 | — | — | WO | disclosed |